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The search parameters are: - Sectors involved in work: 17 IMCA-CAT & XSD
Number of Records: 1513
Publication citations were last updated on 02/01/2026 from Web of Science©

Pravien D. Abeywickrema, Sangita B. Patel, Noel J. Byrne, Ronald E. Diehl, Dawn L. Hall, Rachael E. Ford, Keith W. Rickert, John C. Reid, Jennifer M. Shipman, Wayne M. Geissler, Kelly D. Pryor, Ranabir SinhaRoy, Stephen M. Soisson, Kevin J. Lumb, Sujata Sharma, "Expression, purification and crystallization of human prolylcarboxypeptidase," Acta Crystallogr. F 66 (6), 702-705 (2010). DOI: 10.1107/S1744309110014041 Cited 16 times

Ayome Abibi, Andrew D. Ferguson, Paul R. Fleming, Ning Gao, Laurel I. Hajec, Jun Hu, Valerie A. Laganas, David C. McKinney, Sarah M. McLeod, D.Bryan Prince, Adam B. Shapiro, Ed T. Buurman, "The Role of a Novel Auxiliary Pocket in Bacterial Phenylalanyl-tRNA Synthetase Druggability," J. Biol. Chem. 289 (31), 21651-21662 (2014). DOI: 10.1074/jbc.M114.574061 Cited 21 times

Kim K. Adkison, David G. Barrett, David N. Deaton, Robert T. Gampe, Anne M. Hassell, Stacey T. Long, Robert B. McFadyen, Aaron B. Miller, Larry R. Miller, J. Alan Payne, Lisa M. Shewchuk, Kevin J. Wells-Knecht, Derril H. Willard, Jr., Lois L. Wright, "Semicarbazone-based inhibitors of cathepsin K, are they prodrugs for aldehyde inhibitors?," Bioorg. Med. Chem. Lett. 16 (4), 978-983 (2006). DOI: 10.1002/chin.200620217 Cited 13 times

H.U. Ahmed, M.P. Blakeley, M. Cianci, D.W. J. Cruickshank, J.A. Hubbard, J.R. Helliwell, "The determination of protonation states in proteins," Acta Crystallogr. D 63 (8), 906-922 (2007). DOI: 10.1107/S0907444907029976 Cited 75 times

Kay Ahn, Markus Boehm, Matthew F. Brown, Jessica Calloway, Ye Che, Jinshan Chen, Kimberly F. Fennell, Kieran F. Geoghegan, Adam M. Gilbert, Jemy A. Gutierrez, Amit S. Kalgutkar, Adhiraj Lanba, Chris Limberakis, Thomas V. Magee, Inish O’Doherty, Robert Oliver, Brandon Pabst, Jayvardhan Pandit, Kevin Parris, Jeffrey A. Pfefferkorn, Timothy P. Rolph, Rushi Patel, Brandon Schuff, Veerabahu Shanmugasundaram, Jeremy T. Starr, Alison H. Varghese, Nicholas B. Vera, Cecile Vernochet, Jiangli Yan, "Discovery of a Selective Covalent Inhibitor of Lysophospholipase-like 1 (LYPLAL1) as a Tool to Evaluate the Role of this Serine Hydrolase in Metabolism," ACS Chem. Biol. 11 (9), 2529-2540 (2016). DOI: 10.1021/acschembio.6b00266 Cited 18 times

Adwoa Akwabi-Ameyaw, Jonathan Y. Bass, Richard D. Caldwell, Justin A. Caravella, Lihong Chen, Katrina L. Creech, David N. Deaton, Kevin P. Madauss, Harry B. Marr, Robert B. McFadyen, Aaron B. Miller, Frank Navas, III, Derek J. Parks, Paul K. Spearing, Dan Todd, Shawn P. Williams, G. Bruce Wisely, "FXR agonist activity of conformationally constrained analogs of GW 4064," Bioorg. Med. Chem. Lett. 19 (16), 4733-4739 (2009). DOI: 10.1016/j.bmcl.2009.06.062 Cited 59 times

Adwoa Akwabi-Ameyaw, Justin A. Caravella, Lihong Chen, Katrina L. Creech, David N. Deaton, Kevin P. Madauss, Harry B. Marr, Aaron B. Miller, Frank Navas III, Derek J. Parks, Paul K. Spearing, Dan Todd, Shawn P. Williams, G. Bruce Wisely, "Conformationally constrained farnesoid X receptor (FXR) agonists: Alternative replacements of the stilbene," Bioorg. Med. Chem. Lett. 21 (20), 6154-6160 (2011). DOI: 10.1016/j.bmcl.2011.08.034

Alexander E. Aleshin, Ping-Hua Feng, Richard B. Honzatko, Peter J. Reilly, "Crystal Structure and Evolution of a Prokaryotic Glucoamylase," J. Mol. Biol. 327 (1), 61-73 (2003). DOI: 10.1016/S0022-2836(03)00084-6 Cited 69 times

Yousef M.O. Alhammad, Maithri M. Kashipathy, Anuradha Roy, Jean-Philippe Gagné, Peter McDonald, Philip Gao, Louis Nonfoux, Kevin P. Battaile, David K. Johnson, Erik D. Holmstrom, Guy G. Poirier, Scott Lovell, Anthony R. Fehr, "The SARS-CoV-2 Conserved Macrodomain Is a Mono-ADPRibosylhydrolase," J. Virol. 95 (3), e01969 (2021). DOI: 10.1128/JVI.01969-20 Cited 88 times

Samantha J. Allen, Gopal Parthasarathy, Paul L. Darke, Ronald E. Diehl, Rachael E. Ford, Dawn L. Hall, Scott A. Johnson, John C. Reid, Keith W. Rickert, Jennifer M. Shipman, Stephen M. Soisson, Paul Zuck, Sanjeev K. Munshi, Kevin J. Lumb, "Structure and Function of the Hypertension Variant A486V of G Protein-coupled Receptor Kinase 4," J. Biol. Chem. 290 (33), 20360-20373 (2015). DOI: 10.1074/jbc.M115.648907 Cited 16 times

Charlotte M.N. Allerton, Joel T. Arcari, Lisa M. Aschenbrenner, Melissa Avery, Bruce M. Bechle, Mohammad Amin Behzadi, Britton Boras, Leanne M. Buzon, Rhonda D. Cardin, Natasha R. Catlin, Anthony A. Carlo, Karen J. Coffman, Alyssa Dantonio, Heather Eng, Kathleen A. Farley, Rose Ann Ferre, Steven S. Gernhardt, Scott A. Gibson, Samantha E. Greasley, Siennah R. Greenfield, Brett L. Hurst, Amit S. Kalgutkar, Emi Kimoto, Lorraine F. Lanyon, Gabrielle H. Lovett, Yajing Lian, Wei Liu, Luis A.Martínez Alsina, Stephen Noell, R. Scott Obach, Dafydd R. Owen, Nandini C. Patel, Devendra K. Rai, Matthew R. Reese, Hussin A. Rothan, Sylvie Sakata, Matthew F. Sammons, Jean G. Sathish, Raman Sharma, Claire M. Steppan, Jamison B. Tuttle, Patrick R. Verhoest, Liuqing Wei, Qingyi Yang, Irina Yurgelonis, Yuao Zhu, "A Second-Generation Oral SARS-CoV-2 Main Protease Inhibitor Clinical Candidate for the Treatment of COVID-19," J. Med. Chem. 67 (16), 13550-13571 (2024). DOI: 10.1021/acs.jmedchem.3c02469 Cited 34 times

Candice Alleyne, Rupesh P. Amin, Bhavana Bhatt, Elisabetta Bianchi, J. Craig Blain, Nicolas Boyer, Danila Branca, Mark W. Embrey, Sookhee N. Ha, Kelli Jette, Douglas G. Johns, Angela D. Kerekes, Kenneth A. Koeplinger, Derek LaPlaca, Nianyu Li, Beth Murphy, Peter Orth, Alonso Ricardo, Scott Salowe, Kathleen Seyb, Aurash Shahripour, Joseph R. Stringer, Yili Sun, Rodger Tracy, Chengwei Wu, Yusheng Xiong, Hyewon Youm, Hratch J. Zokian, Thomas J. Tucker, "Series of Novel and Highly Potent Cyclic Peptide PCSK9 Inhibitors Derived from an mRNA Display Screen and Optimized via Structure-Based Design," J. Med. Chem. 63 (22), 13796-13824 (2020). DOI: 10.1021/acs.jmedchem.0c01084 Cited 78 times

Ahmad W. Almawi, Laurence Langlois-Lemay, Stephen Boulton, Javier Rodríguez González, Giuseppe Melacini, Damien D’Amours, Alba Guarné, "Distinct surfaces on Cdc5/PLK Polo-box domain orchestrate combinatorial substrate recognition during cell division," Sci. Rep. 10, 3379 (2020). DOI: 10.1038/s41598-020-60344-4 Cited 10 times

Mark J. Ammirati, Kim M. Andrews, David D. Boyer, Anne M. Brodeur, Dennis E. Danley, Shawn D. Doran, Bernard Hulin, Shenping Liu, R. Kirk McPherson, Stephen J. Orena, Janice C. Parker, Jana Polivkova, Xiayang Qiu, Carolyn B. Soglia, Judith L. Treadway, Maria A. VanVolkenburg, Donald C. Wilder, David W. Piotrowski, "(3,3-Difluoro-pyrrolidin-1-yl)-[(2S,4S)-(4-(4-pyrimidin-2-yl-piperazin-1-yl)-pyrrolidin-2-yl]-methanone: A potent, selective, orally active dipeptidyl peptidase IV inhibitor," Bioorg. Med. Chem. Lett. 19 (7), 1991-1995 (2009). DOI: 10.1016/j.bmcl.2009.02.041 Cited 38 times

Mark Ammirati, Scott W. Bagley, Samit K. Bhattacharya, Leonard Buckbinder, Anthony A. Carlo, Rebecca Conrad, Christian Cortes, Robert L. Dow, Matthew S. Dowling, Ayman El-Kattan, Kristen Ford, Cristiano R.W. Guimarães, David Hepworth, Wenhua Jiao, Jennifer LaPerle, Shenping Liu, Allyn Londregan, Paula M. Loria, Alan M. Mathiowetz, Michael Munchhof, Suvi T.M. Orr, Donna N. Petersen, David A. Price, Athanasia Skoura, Aaron C. Smith, Jian Wang, "Discovery of an in Vivo Tool to Establish Proof-of-Concept for MAP4K4-Based Antidiabetic Treatment," ACS Med. Chem. Lett. 6 (11), 1128-1133 (2015). DOI: 10.1021/acsmedchemlett.5b00215

Chunju An, Scott Lovell, Michael R. Kanost, Kevin P. Battaile, Kristin Michel, "Crystal structure of native Anopheles gambiae Serpin-2, a negative regulator of melanization in mosquitos," Proteins 79 (6), 1999-2003 (2011). DOI: 10.1002/prot.23002 Cited 12 times

David R. Anderson, Marvin J. Meyers, William F. Vernier, Matthew W. Mahoney, Ravi G. Kurumbail, Nicole Caspers, Gennadiy I. Poda, John F. Schindler, David B. Reitz, Robert J. Mourey, "Pyrrolopyridine Inhibitors of Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MK-2)," J. Med. Chem. 50 (11), 2647-2654 (2007). DOI: 10.1021/jm0611004 Cited 153 times

David R. Anderson, Marvin J. Meyers, Ravi G. Kurumbail, Nicole Caspers, Gennadiy I. Poda, Scott A. Long, Betsy S. Pierce, Matthew W. Mahoney, Robert J. Mourey, Mihir D. Parikh, "Benzothiophene inhibitors of MK2. Part 2: Improvements in kinase selectivity and cell potency," Bioorg. Med. Chem. Lett. 19 (16), 4882-4884 (2009). DOI: 10.1016/j.bmcl.2009.02.017 Cited 41 times

Gopinadhan N. Anilkumar, Charles A. Lesburg, Oleg Selyutin, Stuart B. Rosenblum, Qingbei Zeng, Yueheng Jiang, Tin-Yau Chan, Haiyan Pu, Henry Vaccaro, Li Wang, Frank Bennett, Kevin X. Chen, Jose Duca, Stephen Gavalas, Yuhua Huang, Patrick Pinto, Mousumi Sannigrahi, Francisco Velazquez, Srikanth Venkatraman, Bancha Vibulbhan, Sony Agrawal, Nancy Butkiewicz, Boris Feld, Eric Ferrari, Zhiqing He, Chuan-kui Jiang, Robert E. Palermo, Patricia Mcmonagle, H.-C. Huang, Neng-Yang Shih, George Njoroge, Joseph A. Kozlowski, "I. Novel HCV NS5B polymerase inhibitors: Discovery of indole 2-carboxylic acids with C3-heterocycles," Bioorg. Med. Chem. Lett. 21 (18), 5336-5341 (2011). DOI: 10.1016/j.bmcl.2011.07.021 Cited 48 times

Gopinadhan N. Anilkumar, Oleg Selyutin, Stuart B. Rosenblum, Qingbei Zeng, Yueheng Jiang, Tin-Yau Chan, Haiyan Pu, Li Wang, Frank Bennett, Kevin X. Chen, Charles A. Lesburg, Jose Duca, Stephen Gavalas, Yuhua Huang, Patrick Pinto, Mousumi Sannigrahi, Francisco Velazquez, Srikanth Venkatraman, Bancha Vibulbhan, Sony Agrawal, Eric Ferrari, Chuan-kui Jiang, H.-C. Huang, Neng-Yang Shih, F.George Njoroge, Joseph A. Kozlowski, "II. Novel HCV NS5B polymerase inhibitors: Discovery of indole C2 acyl sulfonamides," Bioorg. Med. Chem. Lett. 22 (1), 713-717 (2012). DOI: 10.1016/j.bmcl.2011.10.041

Ashok Arasappan, F. George Njoroge, Tejal N. Parekh, Xiaozheng Yang, John Pichardo, Nancy Butkiewicz, Andrew Prongay, Nanhua Yao, Viyyoor Girijavallabhan, "Novel 2-oxoimidazolidine-4-carboxylic acid derivatives as Hepatitis C virus NS3-4A serine protease inhibitors: synthesis, activity, and X-ray crystal structure of an enzyme inhibitor complex," Bioorg. Med. Chem. Lett. 14 (23), 5751-5755 (2004). DOI: 10.1016/j.bmcl.2004.09.058 Cited 15 times

Julia K. Archbold, Whitney A. Macdonald, Stephanie Gras, Lauren K. Ely, John J. Miles, Melissa J. Bell, Rebekah M. Brennan, Travis Beddoe, Matthew C.J. Wilce, Craig S. Clements, Anthony W. Purcell, James McCluskey, Scott R. Burrows, Jamie Rossjohn, "Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition," J. Exp. Med. 206 (1), 209-219 (2009). DOI: 10.1084/jem.20082136 Cited 84 times

Maria A. Argiriadi, Tao Xiang, Chengbin Wu, Tariq Ghayur, David W. Borhani, "Unusual Water-mediated Antigenic Recognition of the Proinflammatory Cytokine Interleukin-18," J. Biol. Chem. 284 (36), 24478-24489 (2009). DOI: 10.1074/jbc.M109.023887 Cited 26 times

Maria A. Argiriadi, Anna M. Ericsson, Christopher M. Harris, David L. Banach, David W. Borhani, David J. Calderwood, Megan D. Demers, Jennifer DiMauro, Richard W. Dixon, Jennifer Hardman, Silvia Kwak, Biqin Li, John A. Mankovich, Douglas Marcotte, Kelly D. Mullen, Baofu Ni, M. Pietras, Ramkrishna Sadhukhan, Silvino Sousa, Medha J. Tomlinson, L. Wang, T. Xiang, R.V. Talanian, "2,4-Diaminopyrimidine MK2 inhibitors. Part I: Observation of an unexpected inhibitor binding mode," Bioorg. Med. Chem. Lett. 20 (1), 330-333 (2010). DOI: 10.1016/j.bmcl.2009.10.102 Cited 20 times

Maria A. Argiriadi, Eric R. Goedken, David Banach, David W. Borhani, Andrew Burchat, Richard W. Dixon, Doug Marcotte, Gary Overmeyer, Valerie Pivorunas, Ramkrishna Sadhukhan, Silvino Sousa, Nigel St. John Moore, Medha Tomlinson, Jeffrey Voss, Lu Wang, Neil Wishart, Kevin Woller, Robert V. Talanian, "Enabling structure-based drug design of Tyk2 through co-crystallization with a stabilizing aminoindazole inhibitor," BMC Struct. Biol. 12, 22-1-22-11 (2012). DOI: 10.1186/1472-6807-12-22 Cited 16 times

Maria A. Argiriadi, David Banach, Elzbieta Radziejewska, Susan Marchie, Jennifer DiMauro, Jurgen Dinges, Eric Dominguez, Charles Hutchins, Russell A. Judge, Kara Queeney, Grier Wallace, Christopher M. Harris, "Creation of a S1P Lyase bacterial surrogate for structure-based drug design," Bioorg. Med. Chem. Lett. 26 (9), 2293-2296 (2016). DOI: 10.1016/j.bmcl.2016.02.084 Cited 10 times

Maria A. Argiriadi, Lorenzo Benatuil, Ievgeniia Dubrovska, David A. Egan, Lei Gao, Amy Greischar, Jennifer Hardman, John Harlan, Ramesh B. Iyer, Russell A. Judge, Marc Lake, Denise C. Perron, Ramkrishna Sadhukhan, Bernhard Sielaff, Silvino Sousa, Rui Wang, Bradford L. McRae, "CD40/anti-CD40 antibody complexes which illustrate agonist and antagonist structural switches," BMC Mol. Cell Biol. 20, 29-1-29 (2019). DOI: 10.1186/s12860-019-0213-4 Cited 20 times

Rishi Arora, Amitabh V. Nimonkar, Daniel Baird, Chunhua Wang, Chun-Hao Chiu, Patricia A. Horton, Susan Hanrahan, Rose Cubbon, Stephen Weldon, William R. Tschantz, Sascha Mueller, Reto Brunner, Philipp Lehr, Peter Meier, Johannes Ottl, Andrei Voznesensky, Pramod Pandey, Thomas M. Smith, Aleksandar Stojanovic, Alec Flyer, Timothy E. Benson, Michael J. Romanowski, John W. Trauger, "Structure of lipoprotein lipase in complex with GPIHBP1," Proc. Natl. Acad. Sci. USA 116 (21), 10360-10365 (2019). DOI: 10.1073/pnas.1820171116 Cited 51 times

Rishi Arora, Chong Wai Liew, Tingjin Sherryl Soh, Dorcas Adobea Otoo, Cheah Chen Seh, Kimberley Yue, Shahul Nilar, Gang Wang, Fumiaki Yokokawa, Christian G. Noble, Yen Liang Chen, Pei-Yong Shi, Julien Lescar, Thomas M. Smith, Timothy E. Benson, Siew Pheng Lim, "Two RNA Tunnel Inhibitors Bind in Highly Conserved Sites in Dengue Virus NS5 Polymerase: Structural and Functional Studies," J. Virol. 94 (24), e01130 (2020). DOI: 10.1128/JVI.01130-20 Cited 22 times

Emilia Cristina Arturo, "The study and manipulation of the structures of mammalian phenylalanine hydroxylase (PAH)," Ph.D., Drexel University, 2018.

Ernest Asante-Appiah, Sangita Patel, Claude Dufresne, Patrick Roy, Qingping Wang, Vira Patel, Richard W. Friesen, Chidambaram Ramachandran, Joseph W. Becker, Yves Leblanc, Brian P. Kennedy, Giovanna Scapin, "The structure of PTP-1B in complex with a peptide inhibitor reveals an alternative binding mode for bisphosphonates," Biochemistry-US 41, 9043-9051 (2002). Cited 55 times

Ernest Asante-Appiah, Sangita Patel, Caroline Desponts, Jillian M. Taylor, Cheuk Lau, Claude Dufresne, Michel Therien, Rick Friesen, Joseph W. Becker, Yves Leblanc, Brian P. Kennedy, Giovanna Scapin, "Conformation-assisted Inhibition of Protein-tyrosine Phosphatase-1B Elicits Inhibitor Selectivity over T-cell Protein-tyrosine Phosphatase," J. Biol. Chem. 281 (12), 8010-8015 (2006). DOI: 10.1074/jbc.M511827200 Cited 41 times

Emily B. Askew, Robert T. Gampe, Jr., Thomas B. Stanley, Jonathan L. Faggart, Elizabeth M. Wilson, "Modulation of Androgen Receptor Activation Function 2 by Testosterone and Dihydrotestosterone," J. Biol. Chem. 282 (35), 25801-25816 (2007). DOI: 10.1074/jbc.M703268200 Cited 166 times

Renee Aspiotis, Austin Chen, Elizabeth Cauchon, Daniel Dubé, Jean-Pierre Falgueyret, Sébastien Gagné, Michel Gallant, Erich L. Grimm, Robert Houle, Hélène Juteau, Patrick Lacombe, Sébastien Laliberté, Jean-François Lévesque, Dwight MacDonald, Dan McKay, M. David Percival, Patrick Roy, Stephen M. Soisson, Tom Wu, "The discovery and synthesis of potent zwitterionic inhibitors of renin," Bioorg. Med. Chem. Lett. 21 (8), 2430-2436 (2011). DOI: 10.1016/j.bmcl.2011.02.067 Cited 9 times

Genevieve Asselin, Yang Wei, Leslie Gates, Yang Wang, Junwei Lucas Bao, Wenqian Xu, Niya Sa, "Bridging Atomic Solvation Environment with Electrochemical Properties for the Bis(trifluoromethylsulfonyl)imide-Based Divalent Cation Electrolytes for the Next-Generation Energy Storage Systems," ACS Appl. Mater. Interfaces 17 (9), 13916-13927 (2025). DOI: 10.1021/acsami.4c20787

Zeynep Akyol Ataman, Lokesh Gakhar, Brenda R. Sorensen, Johannes W. Hell, Madeline A. Shea, "The NMDA Receptor NR1 C1 Region Bound to Calmodulin: Structural Insights into Functional Differences between Homologous Domains," Structure 15, 1603-1617 (2007). DOI: 10.1016/j.str.2007.10.012 Cited 73 times

Douglas S. Auld, Scott Lovell, Natasha Thorne, Wendy A. Lea, David J. Maloney, Min Shen, Ganesha Rai, Kevin P. Battaile, Craig J. Thomas, Anton Simeonov, Robert P. Hanzlik, James Inglese, "Molecular basis for the high-affinity binding and stabilization of firefly luciferase by PTC124," Proc. Natl. Acad. Sci. USA 107 (11), 4878-4883 (2010). DOI: 10.1073/pnas.0909141107 Cited 154 times

Arezki Azzi, Shawn A. Clark, W. Ross Ellington, Michael S. Chapman, "The role of phosphagen specificity loops in arginine kinase," Protein Sci. 13, 575-585 (2004). Cited 61 times

Holger Babbe, Thomas B. Sundberg, Mark Tichenor, Mark Seierstad, Genesis Bacani, James Berstler, Wenying Chai, Leon Chang, De Michael Chung, Kevin Coe, Bernard Collins, Michael Finley, Alexander Guletsky, Christopher T. Lemke, Puiying A. Mak, Ashok Mathur, Eduardo V. Mercado-Marin, Shailesh Metkar, Donald D. Raymond, Marie-Laure Rives, Michele Rizzolio, Paul L. Shaffer, Russell Smith, Jacqueline Smith, Ruth Steele, Helena Steffens, Javier Suarez, Gaochao Tian, Nathan Majewski, Laurie P. Volak, Jianmei Wei, Prerak T. Desai, Luvena L. Ong, Tatiana Koudriakova, Steven D. Goldberg, Gavin Hirst, Virendar K. Kaushik, Tatiana Ort, Nilufer Seth, Daniel B. Graham, Scott Plevy, Jennifer D. Venable, Ramnik J. Xavier, Jennifer E. Towne, "Identification of highly selective SIK1/2 inhibitors that modulate innate immune activation and suppress intestinal inflammation," Proc. Natl. Acad. Sci. USA 121 (1), e2307086120 (2023). DOI: 10.1073/pnas.2307086120 Cited 13 times

Bradley J. Backes, Kenton Longenecker, Gregory L. Hamilton, Kent Stewart, Chunqiu Lai, Hana Kopecka, Thomas W. von Geldern, David J. Madar, Zhonghua Pei, Thomas H. Lubben, Bradley A. Zinker, Zhenping Tian, Stephen J. Ballaron, Michael A. Stashko, Amanda K. Mika, David W.A. Beno, Anita J. Kempf-Grote, Candace Black-Schaefer, Hing L. Sham, James M. Trevillyan, "Pyrrolidine-constrained phenethylamines: The design of potent, selective, and pharmacologically efficacious dipeptidyl peptidase IV (DPP4) inhibitors from a lead-like screening hit," Bioorg. Med. Chem. Lett. 17 (7), 2005-2012 (2007). DOI: 10.1016/j.bmcl.2007.01.026 Cited 34 times

Brian Bae, Yi-Hsing Chen, Alessandro Costa, Silvia Onesti, Joseph S. Brunzelle, Yuyen Lin, Isaac K.O. Cann, Satish K. Nair, "Insights into the Architecture of the Replicative Helicase from the Structure of an Archaeal MCM Homolog," Structure 17 (2), 211-222 (2009). DOI: 10.1016/j.str.2008.11.010 Cited 44 times

Kyuwon Baek, Xiong Liu, Francois Ferron, Shi Shu, Edward D. Korn, Roberto Dominguez, "Modulation of actin structure and function by phosphorylation of Tyr-53 and profilin binding," Proc. Natl. Acad. Sci. USA 105 (33), 11748-11753 (2008). DOI: 10.1073/pnas.0805852105 Cited 48 times

Kyuwon Baek, Andreas Knödler, Sung Haeng Lee, Xiaoyu Zhang, Kelly Orlando, Jian Zhang, Trevor J. Foskett, Wei Guo, Roberto Dominguez, "Structure-Function Study of the N-terminal Domain of Exocyst Subunit Sec3," J. Biol. Chem. 285 (14), 10424-10433 (2010). DOI: 10.1074/jbc.M109.096966 Cited 47 times

Sharan K. Bagal, Mark Andrews, Bruce M. Bechle, Jianwei Bian, James Bilsland, David C. Blakemore, John F. Braganza, Peter J. Bungay, Matthew S. Corbett, Ciaran N. Cronin, Jingrong Jean Cui, Rebecca Dias, Neil J. Flanagan, Samantha E. Greasley, Rachel Grimley, Kim James, Eric Johnson, Linda Kitching, Michelle L. Kraus, Indrawan McAlpine, Asako Nagata, Sacha Ninkovic, Kiyoyuki Omoto, Stephanie Scales, Sarah E. Skerratt, Jianmin Sun, Michelle Tran-Dubé, Gareth J. Waldron, Fen Wang, Joseph S. Warmus, "Discovery of Potent, Selective, and Peripherally Restricted Pan-Trk Kinase Inhibitors for the Treatment of Pain," J. Med. Chem. 61 (15), 6779-6800 (2018). DOI: 10.1021/acs.jmedchem.8b00633 Cited 29 times

Sharan K. Bagal, Kiyoyuki Omoto, David C. Blakemore, Peter J. Bungay, James G. Bilsland, Philip J. Clarke, Matthew S. Corbett, Ciaran N. Cronin, J. Jean Cui, Rebecca Dias, Neil J. Flanagan, Samantha E. Greasley, Rachel Grimley, Eric Johnson, David Fengas, Linda Kitching, Michelle L. Kraus, Indrawan McAlpine, Asako Nagata, Gareth J. Waldron, Joseph S. Warmus, "Discovery of Allosteric, Potent, Subtype Selective, and Peripherally Restricted TrkA Kinase Inhibitors," J. Med. Chem. 62 (1), 247-265 (2019). DOI: 10.1021/acs.jmedchem.8b00280 Cited 42 times

Jeffrey T. Bagdanoff, Zhouliang Chen, Michael Acker, Ying-Nan Chen, Homan Chan, Michael Dore, Brant Firestone, Michelle Fodor, Jorge Fortanet, Murphy Hentemann, Mitsunori Kato, Robert Koenig, Laura R. LaBonte, Shumei Liu, Movarid Mohseni, Rukundo Ntaganda, Patrick Sarver, Troy Smith, Martin Sendzik, Travis Stams, Stan Spence, Christopher Towler, Hongyun Wang, Ping Wang, Sarah L. Williams, Matthew J. LaMarche, "Optimization of Fused Bicyclic Allosteric SHP2 Inhibitors," J. Med. Chem. 62 (4), 1781-1792 (2019). DOI: 10.1021/acs.jmedchem.8b01725 Cited 72 times

Saket R. Bagde, Irimpan I. Mathews, J. Christopher Fromme, Chu-Young Kim, "Modular polyketide synthase contains two reaction chambers that operate asynchronously," Science 374, 723-729 (2021). DOI: 10.1126/science.abi8532 Cited 50 times

Yonghong Bai, Jason G. McCoy, Elena J. Levin, Pablo Sobrado, Kanagalaghatta R. Rajashankar, Brian G. Fox, Ming Zhou , "X-ray structure of a mammalian stearoyl-CoA desaturase," Nature 524, 252-256 (2015). DOI: 10.1038/nature14549 Cited 192 times

Keith D. Baker, Lisa M. Shewchuk, Tatiana Kozlova, Makoto Makishima, Annie Hassell, Bruce Wisely, Justin A. Caravella, Millard H. Lambert, Jeffrey L. Reinking, Henry Krause, Carl S. Thummel, Timothy M. Willson, David J. Mangelsdorf, "The Drosophila orphan nuclear receptor DHR38 mediates an atypical ecdysteroid signaling pathway," Cell 113 (6), 731-742 (2003). Cited 195 times

Majida El Bakkouri, Andre Pow, Anne Mulichak, Kevin L.Y. Cheung, Jennifer D. Artz, Mehrnaz Amani, Stuart Fell, Tania F. de Koning-Ward, C. Dean Goodman, Geoffrey I. McFadden, Joaquin Ortega, Raymond Hui, Walid A. Houry, "The Clp Chaperones and Proteases of the Human Malaria Parasite Plasmodium falciparum," J. Mol. Biol. 404 (3), 456-477 (2010). DOI: 10.1016/j.jmb.2010.09.051 Cited 70 times

Sumirtha Balaratnam, Zachary R. Torrey, David R. Calabrese, Michael T. Banco, Kamyar Yazdani, Xiao Liang, Christopher R. Fullenkamp, Srinath Seshadri, Ronald J. Holewinski, Thorkell Andresson, Adrian R. Ferré-D'Amaré, Danny Incarnato, John S. Schneekloth Jr., "Investigating the NRAS 5′ UTR as a target for small molecules," Cell Chem. Biol. 30 (6), 643-657 (2023). DOI: 10.1016/j.chembiol.2023.05.004 Cited 19 times

Eric T. Baldwin, Melissa S. Harris, Anthony W. Yem, Cindy L. Wolfe, Anne F. Vosters, Kimberly A. Curry, Robert W. Murray, Jeffrey H. Bock, Vincent P. Marshall, Joyce I. Cialdella, Mahesh H. Merchant, Gil Choi, Martin R. Diebel, Jr., "Crystal structure of type II peptide deformylase from Staphylococcus aureus," J. Biol. Chem. 277 (34), 31163-31171 (2002). Cited 44 times

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Shu-Hui Chen, Jason Lamar, Deqi Guo, Todd Kohn, Hsiu-Chiung Yang, James McGee, David Timm, Jon Erickson, Yvonne Yip, Patrick May, James McCarthy, "P3 cap modified Phe*-Ala series BACE inhibitors," Bioorg. Med. Chem. Lett. 14, 245-250 (2004). Cited 37 times

Kevin X. Chen, F. George Njoroge, Bancha Vibulbhan, Andrew Prongay, John Pichardo, Vincent Madison, Alexei Buevich, Tze-Ming Chan, "Proline-Based Macrocyclic Inhibitors of the Hepatitis C Virus: Stereoselective Synthesis and Biological Activity," Angew. Chem. Int. Ed. 44 (43), 7024-7028 (2005). DOI: 10.1002/anie.200501553 Cited 20 times

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Ping Chen, Ya-Li Deng, Simon Bergqvist, Matthew D. Falk, Wei Liu, Sergei Timofeevski, Alexei Brooun, "Engineering of an isolated p110[alpha] subunit of PI3K[alpha] permits crystallization and provides a platform for structure-based drug design," Protein Sci. 23 (10), 1332-1340 (2014). DOI: 10.1002/pro.2517 Cited 25 times

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Ying-Nan P. Chen, Matthew J. LaMarche, Ho Man Chan, Peter Fekkes, Jorge Garcia-Fortanet, Michael G. Acker, Brandon Antonakos, Christine Hiu-Tung Chen, Zhouliang Chen, Vesselina G. Cooke, Jason R. Dobson, Zhan Deng, Feng Fei, Brant Firestone, Michelle Fodor, Cary Fridrich, Hui Gao, Denise Grunenfelder, Huai-Xiang Hao, Jaison Jacob, Samuel Ho, Kathy Hsiao, Zhao B. Kang, Rajesh Karki, Mitsunori Kato, Jay Larrow, Laura R. La Bonte, Francois Lenoir, Gang Liu, Shumei Liu, Dyuti Majumdar, Matthew J. Meyer, Mark Palermo, Lawrence Perez, Minying Pu, Edmund Price, Christopher Quinn, Subarna Shakya, Michael D. Shultz, Joanna Slisz, Kavitha Venkatesan, Ping Wang, Markus Warmuth, Sarah Williams, Guizhi Yang, Jing Yuan, Ji-Hu Zhang, Ping Zhu, Timothy Ramsey, Nicholas J. Keen, William R. Sellers, Travis Stams, Pascal D. Fortin , "Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases," Nature 535, 148-152 (2016). DOI: 10.1038/nature18621 Cited 692 times

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