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Advanced Photon Source

A U.S. Department of Energy, Office of Science,
Office of Basic Energy Sciences national synchrotron x-ray research facility

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APS Beamline Directory

Beamline Information Maintenance

Beamline 17-ID-B: Sector 17 - Insertion Device

IMCA-CAT
Life Sciences

Description

Optimized for proprietary structure-based drug design, IMCA-CAT is dedicated to high-throughput macromolecular crystallography for the pharmaceutical industry. The beamline is equipped with industrial-strength high-speed robotics and automated for sample mounting, diffraction centering, data acquisition, and data processing. Mail-in access, only.

 

Supported Techniques

  • Macromolecular crystallography
  • Multi-wavelength anomalous dispersion
  • Microbeam
  • Single-wavelength anomalous dispersion
  • Large unit cell crystallography
  • Subatomic (<0.85 Å) resolution

Beamline Controls and Data Acquisition

Epics; GUI for beamline control (including energy or wavelength, energy scans for MAD, attenuation, beam size); auto and manual data collection; Global Phasing autoPROC for auto data processing; and SynchWeb/ISPyB for communicating sample information.

Detectors

  • Dectris Eiger2 X 9M Pixel Array
  • Rontec X-Flash SDD for fluorescence spectroscopy

Additional Equipment

  • Rigaku ACTOR2S industrial robot (Unipucks only; capacity for 672 samples)
  • Oxford Instruments cryojet
  • AIM Concepts air bearing goniometer
  • On-axis sample visualization system
  • Automatic filling of liquid nitrogen dewars
  • User-accessible computers for data processing
  • Biochemistry Laboratory for sample preparation
  • >60 TB Storage System

Local Contacts

Name LISA J KEEFE
Phone 630.252.0544

Beamline Specs

Source

3.3 Undulator (Undulator A)

Monochromator Type

Si(111)

Energy Range

6-20 keV

Resolution (ΔE/E)

1.5 x 10 -4

Flux (photons/sec)

8 x 10 12 @12.4 keV

Beam Size (HxV)

Focused

5µm x 5µm

For additional information see:
https://www.imca-cat.org

Current Status:

Commissioning

Access Mode:

Mail-in
Last Updated on 01/07/2025
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